Radiopharmacist (Fedoruk Centre) (req4357)
The University of Saskatchewan values diversity, and Indigenous engagement is a strategic priority.
Posted Date: 5/16/2019
Number of Openings: 1
The Sylvia Fedoruk Canadian Centre for Nuclear Innovation Inc. (Fedoruk Centre) is inviting applications for a Radiopharmacist: (a) to ensure quality control and safety of novel radiopharmaceuticals, in compliance with regulations of Health Canada and the Canadian Nuclear Safety Commission; and (b) to provide collaborative scientific support for researchers who access the specialized facilities at the Saskatchewan Centre for Cyclotron Sciences (SCCS) to advance their programs of innovation in nuclear imaging or therapy towards clinical applications.
The Fedoruk Centre was established in 2011 under the Canada Not-for-Profit Corporations Act, with an independent Board of Directors and a sole Member, the University of Saskatchewan (U Sask). The purpose of the Fedoruk Centre is to help place Canada among global leaders of nuclear research, development and training through investment in partnerships with academia and industry. The SCCS is owned by U Sask and operated by the Fedoruk Centre. Commencing operation in 2015, this $25 million facility features a high-current ACSI TR24 cyclotron; a cGMP-level radiopharmaceutical laboratory including hot cells, auto-synthesis units and a quality control system (HPLC, GC, TLC); and a small-animal SPECT-PET-CT scanner for preclinical research. An additional investment of $5M was secured from provincial and federal agencies in 2018 to establish an innovation complex of shielded work areas, radiochemistry equipment and a new high-throughput PET-CT instrument, for access by users to develop new nuclear imaging agents for disease-targeting diagnoses and treatments. Besides serving as a centre of scientific collaborations and partnerships among the province’s two universities, the Saskatchewan Health Authority and industry, the SCCS supplies fludeoxyglucose (FDG) for PET-CT scanning at the Royal University Hospital in Saskatoon, enabling more than 2500 patients each year to receive medical scans for diagnosis of cancer. The SCCS is licensed by the Canadian Nuclear Safety Commission (CNSC) as a Class II Nuclear Facility. Radiopharmaceuticals are manufactured in compliance with regulations of the CNSC and Health Canada.
The salary range for this Radiopharmacist position is $87,000 - $145,750 per annum. Placement within the range is dependent upon education and experience. This is a continuing full-time position that is not within any collective bargaining unit.
Please submit a covering letter and resume in PDF format by email to email@example.com, with Subject Line: Radiopharmacist; [your name].
This position will be posted until filled. Screening will begin on/about July 2, 2019. The start date for employment will be as mutually agreed. While the Fedoruk Centre thanks all applicants for their interest, only short-listed candidates will be contacted.
Inquiries regarding this position may be directed to:
Niki Schrie, Human Resources and Operations Manager
Primary Purpose: The Radiopharmacist is responsible (a) to ensure quality control and safety of novel radiopharmaceuticals, in compliance with regulations of Health Canada and the Canadian Nuclear Safety Commission; and (b) to provide collaborative scientific support for researchers who access the specialized facilities at the Saskatchewan Centre for Cyclotron Sciences (SCCS) to advance their programs of innovation in nuclear imaging or therapy towards clinical applications
Nature of Work: Reporting to the SCCS Facility Manager, the Radiopharmacist is part of a team that manufactures PET imaging agents for medical diagnoses and treatments in regional hospitals, and will increasingly support the development of novel radiopharmaceuticals for preclinical and clinical trials, among other applications in life sciences. The SCCS is equipped with an ACSI TR24 cyclotron; a cGMP-level radiopharmaceutical laboratory including hot cells, auto-synthesis units and a quality control system (HPLC, GC, TLC); small-animal SPECT-PET-CT scanners for preclinical research; shielded work areas, and radiochemistry equipment. Most of these facilities are accessible by users from academia and industry to develop new nuclear imaging agents for disease-targeting diagnoses and treatments. The radiopharmacist will be responsible for ensuring full compliance with quality regulations while addressing specifications of research leaders and customers. The position will hold a key responsibility to advise SCCS management, staff and users about risks of adverse reactions or issues of quality, and to take the lead in risk mitigations. The position will also serve as a professional “Local Contact” for SCCS facility users to undertake research projects effectively, accommodating the experience-levels of users, and resources needed for each project, considering project planning, implementation, analysis and reporting.
The primary work environment is the suite of offices and labs in the Saskatchewan Centre for Cyclotron Sciences at 120 Maintenance Rd, Saskatoon, Saskatchewan.
- Participating in the design and development of novel radiopharmaceutical production to ensure processes are aligned with industry guidelines and regulations;
- Managing product complaints, recalls and adverse drug reaction assessments and the submissions of related reports to Health Canada;
- Liaising with researchers to provide Quality Assurance and Regulatory Affairs support;
- Collaborating with research users to plan, implement, analyze and report scientific projects;
- Maintaining Quality Assurance standards and ensuring compliance with regulatory authorizations;
- Performing related duties that support the core activities and mission of the Fedoruk Centre.
- Masters or PhD in radiopharmacy, radiochemistry or a Masters or PhD in organic or medicinal chemistry is required.
- At least three years of post-educational working experience in a radiopharmacy or radiopharmaceutical production facility or radiopharmaceutical research laboratory is required.
- Experience in process development or manufacturing at a SPR or PER radiopharmacy laboratory is required.
- Experience in Quality Assurance and/or Regulatory Affairs is required.
- Experience in safe handling of radioactive materials and radiation protection is required.
- Working knowledge of Canada’s regulatory framework relevant to radiopharmaceuticals, including radiation safety regulations of the Canadian Nuclear Safety Commission (CNSC) and Good Manufacturing Practice (GMP) for Positron-Emitting Radiopharmaceuticals (PERs), compliant with Health Canada regulations;
- Working knowledge of safe handling of radionuclides and radiochemistry;
- Basic understanding of drug development, preclinical and clinical testing and steps to bring a new product to the marketplace;
- Demonstrated ability to identify risks in safety or compliance and a working knowledge of how to respond appropriately when an issue is discovered.
- Fosters a safe and respectful workplace culture through leadership and example;
- Works independently, making decisions based on judgment and integrity;
- Promotes teamwork in a diverse, multidisciplinary environment;
- Focuses on delivering commitments to clients and users, subject to organizational plans and priorities, as well as regulatory constraints;
- Communicates information and ideas clearly to an audience, to achieve understanding, retention and response to the message;
- Reflects, clarifies, and commits to what is important, taking responsibility for growth and development, and fostering a positive environment for work and learning.
Condition: Any offer of employment will be conditional on the results of a medical assessment and/or vision examination to the extent permissible under employment law (The Saskatchewan Employment Act, S-15.1, 2013, as amended).
The University of Saskatchewan is strongly committed to a diverse and inclusive workplace that empowers all employees to reach their full potential. All members of the university community share a responsibility for developing and maintaining an environment in which differences are valued and inclusiveness is practiced. The university welcomes applications from those who will contribute to the diversity of our community. The University must, however, comply with federal immigration requirements. All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.