The Sylvia Fedoruk Canadian Centre for Nuclear Innovation (Fedoruk Centre) is inviting applications for a Radiopharmacist to support the research and manufacture of radiopharmaceuticals at the Saskatchewan Centre for Cyclotron Sciences (SCCS). The complete job profile is attached.
The SCCS is owned by the University of Saskatchewan (U of S) and operated by the Fedoruk Centre. This new $25 million facility features a high-current ACSI TR24 cyclotron; a cGMP-level radiopharmaceutical laboratory including hot cells, auto-synthesis units and a quality control system (HPLC, GC, TLC); and a suite of offices, all located in 1400 square meters of newly renovated space co-located with 600 square meters of additional space to be developed in support of related research activities. It is licensed by the Canadian Nuclear Safety Commission as a Class II Nuclear Facility, and its core activity is the production of imaging probes and associated technologies for applications in human, animal and plant research and in medical care. This key infrastructure resource will be the centre of collaborations and partnerships among the province’s two universities, the provincial health regions and industry, and currently supplies fludeoxyglucose (FDG) for PET-CT scanning at the Royal University Hospital in Saskatoon, daily.
A wholly owned subsidiary of the University of Saskatchewan, the Fedoruk Centre operates independently under the Canada Not-for-Profit Corporations Act. The Fedoruk Centre and SCCS are located in Saskatoon, Saskatchewan.
The salary range is $87,000 - $145,750 per annum. Placement within the range is dependent upon education and experience. This is a continuing full-time position. This position is not within any collective bargaining unit.
How to Apply
See the attached Job Profile for detailed qualifications and job description. Please submit a covering letter and resume in PDF format by email to email@example.com, with Subject Line: Radiopharmacist; [your name].
This position will be posted until filled. Screening will begin on/about October 30, 2018, with the start date to be mutually agreed upon. While the Fedoruk Centre thanks all applicants for their interest, only short-listed candidates will be contacted.
Inquiries regarding this position may be directed to:
The Fedoruk Centre is committed to a diverse and inclusive workplace. All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.
Job Profile: Radiopharmacist
PRIMARY PURPOSE: The Radiopharmacist is responsible for ensuring radiopharmaceutical product quality (Canadian regulations for Good Manufacturing Practices) in both clinical and research settings, as well as to support translational research by academic or industry users of facilities in the Saskatchewan Centre for Cyclotron Sciences.
NATURE OF WORK: Reporting to the SCCS Facility Manager, the Radiopharmacist is part of a team that manufactures PET imaging agents for medical diagnoses and treatments in regional hospitals, along with supporting the development of novel radiopharmaceuticals for preclinical and clinical trials, among other applications in life sciences. Producing isotopes, radiochemicals and radiopharmaceuticals, as well as nuclear imaging of living specimens, are all supported by specialized facilities and expertise in the Saskatchewan Centre for Cyclotron Sciences (SCCS). The SCCS is equipped with an ACSI TR-24 cyclotron, Positron Emitting Radiopharmaceutical (PER) production laboratories (for both research-grade and Health Canada-compliant grade handling of PERs), as well as a cold chemistry laboratory and a PET-imaging facility. Responsibilities for the radiopharmacist include optimizing the radiopharmaceutical chemistry operations for PERs as well as participating in the production and development of research radionuclides and radiopharmaceuticals. The position will be responsible for ensuring full compliance with quality regulations and customer specifications. The position will hold a primary responsibility to advise SCCS management, staff and users about risks of adverse reactions or issues of quality, and to take the lead in risk mitigations.
The primary work environment is the suite of offices and labs in the Saskatchewan Centre for Cyclotron Sciences.
- Developing and optimizing manufacturing processes in order to yield high quality results;
- Assisting in the design and development of novel radiopharmaceutical production to ensure processes are aligned with industry guidelines and regulations;
- Managing product complaints, recalls and adverse drug reaction assessments and the submissions of related reports to Health Canada;
- Liaising with researchers to provide Quality Assurance and Regulatory Affairs support;
- Maintaining Quality Assurance standards and ensuring compliance with regulatory authorizations;
- Performing related duties that support the core activities and mission of the Fedoruk Centre.
- PhD in radiopharmacy, pharmacy, medicinal chemistry, or radiochemistry is required.
- At least three years of post-doctoral experience in a radiopharmacy or radiopharmaceutical production facility or radiopharmaceutical research laboratory is required.
- Prior experience in process development or manufacturing at a SPR or PER radiopharmacy laboratory would be an asset.
- Experience in Quality Assurance and/or Regulatory Affairs would be an asset.
- Knowledge of Canada’s regulatory framework relevant to radiopharmeceuticals, including radiation safety (CNSC) and GMP for PERs Annex (HC);
- Basic understanding of drug development and of the Canadian regulatory environment and Health Canada regulations, policies and guidelines;
- Experience with safe handling of radionuclides and radiochemistry;
- Ability to identify compliance risks and escalate when necessary;
- Fosters a safe and respectful workplace culture through leadership and example;
- Works independently, making decisions based on judgment and integrity;
- Promotes teamwork in a diverse, multidisciplinary environment;
- Focuses on delivering commitments made to stakeholders, subject to organizational plans and priorities, as well as regulatory constraints;
- Communicates information and ideas clearly to an audience, to achieve understanding, retention and response to the message;
- Reflects, clarifies, and commits to what is important, taking responsibility for growth and development, and fostering a positive environment for work and learning.
Any offer of employment will be conditional on the results of a medical assessment and/or vision examination to the extent permissible under employment law (The Saskatchewan Employment Act, S-15.1, 2013, as amended).